Female infertility is a condition that affects millions of women worldwide. It refers to the inability to conceive a child or carry a pregnancy to term due to various factors such as hormonal imbalances, physical abnormalities, and lifestyle choices. While male infertility is also a significant concern, female infertility accounts for approximately 40% of all infertility cases.

Infertility is generally diagnosed when a couple is unable to conceive after one year of trying to conceive without the use of any contraception. If a woman is over the age of 35, infertility may be diagnosed after six months of trying to conceive. Infertility can be a devastating diagnosis for couples who dream of starting a family. However, with proper diagnosis and treatment, many couples are able to overcome infertility and successfully conceive.

Causes of Female Infertility

There are many causes of female infertility, some of which include:

Ovulation Disorders: Ovulation disorders are the most common cause of female infertility. Conditions such as Polycystic Ovary Syndrome (PCOS), premature ovarian failure, and thyroid disorders can affect a woman’s ability to ovulate regularly, making it difficult to conceive.

Uterine or Cervical Abnormalities: Abnormalities in the uterus or cervix can affect a woman’s ability to conceive. Conditions such as uterine fibroids, endometriosis, and blocked fallopian tubes can make it difficult for a fertilized egg to implant in the uterus or for sperm to reach the egg.

Age: Age is an important factor in female fertility. As a woman ages, her fertility decreases due to a decline in the quantity and quality of her eggs. Women over the age of 35 may have a harder time conceiving and may be at increased risk of miscarriage and other pregnancy complications.

Lifestyle Factors: Certain lifestyle factors can also affect female fertility. Smoking, excessive alcohol consumption, and a sedentary lifestyle can all decrease fertility. Being overweight or underweight can also affect fertility.

Pelvic Inflammatory Disease (PID): PID is an infection of the reproductive organs that can cause scarring and blockages, making it difficult for eggs to travel through the fallopian tubes.

Premature Ovarian Failure: Premature ovarian failure occurs when a woman’s ovaries stop functioning before the age of 40, causing a decrease in estrogen and making it difficult to conceive.

Autoimmune Disorders: Certain autoimmune disorders such as lupus or rheumatoid arthritis can affect fertility by causing inflammation and damage to the reproductive organs.

Cancer Treatments: Radiation and chemotherapy treatments for cancer can damage the reproductive organs and decrease fertility.

Medications: Certain medications such as chemotherapy drugs or antidepressants can affect fertility by decreasing ovulation or damaging the reproductive organs.

Stress: Chronic stress can affect fertility by disrupting hormone levels and ovulation.

Diagnosis of Female Infertility

The diagnosis of female infertility typically involves a physical exam, medical history, and various tests to determine the underlying cause of infertility. These tests may include:

Blood Tests: Blood tests can be used to check hormone levels and detect any hormonal imbalances that may be affecting fertility.

Imaging Tests: Imaging tests such as ultrasound or hysterosalpingography (HSG) can be used to check for abnormalities in the uterus or fallopian tubes.

Ovarian Reserve Testing: Ovarian reserve testing can be used to determine the quantity and quality of a woman’s eggs.

Laparoscopy: Laparoscopy is a surgical procedure that can be used to diagnose and treat certain conditions that may be affecting fertility.

Treatment of Female Infertility

The treatment of female infertility depends on the underlying cause of the infertility. Some common treatments include:

Medications: Medications such as clomiphene citrate or gonadotropins can be used to stimulate ovulation and increase the chances of conception.

Surgery: Surgery may be necessary to correct abnormalities such as uterine fibroids or endometriosis that are affecting fertility.

Intrauterine Insemination (IUI): Intrauterine insemination involves the insertion of centrifuged semen  directly into the uterus to increase the chances of conception.

In Vitro Fertilization (IVF): IVF is a procedure that involves the fertilization of eggs outside the body and the subsequent transfer of embryos into the uterus.


With proper diagnosis and treatment, many couples are able to overcome infertility and successfully conceive. It is important for women who are struggling with infertility to seek the help of a fertility specialist and to explore all available treatment options to improve their chances of conception.


Dr Ila Gupta

Director & Sr Consultant
Infertility & IVFSpecialist
Ferticity IVF & Fertilty clinic Delhi