The World Health Organisation (WHO) has established that approximately 3-4% of females suffer from Polycystic Ovary Syndrome(PCOS) globally. Although this data point dates back to 2012, it is only natural that the number would have increased given the changes in lifestyle of women worldwide! With more than 110 million PCOS patients, it has become highly crucial to weigh different options to prevent and cure the disease. It is observed that women with PCOS face difficulty in conceiving. The PCOS pregnancy success rate is not so reputable, and therefore, medical science has come up with alternatives that help induce pregnancy in PCOS patients.
This blog discusses PCOS in detail and its effects on pregnancy. It throws some light on the success rate of Artificial Reproductive Technology (ART), particularly In-vitro Fertilisation (IVF) as an alternative method to get pregnant.
Understanding PCOS and Its Symptoms
Polycystic Ovary Syndrome (PCOS) is an endocrine disorder that is prevalent among women worldwide. It is a multi-factorial disorder, the exact cause of which is unidentifiable. Many probable factors can culminate in triggering PCOS in any reproductive female. These factors include insulin resistance, genetic predisposition, and inflammation.
Insulin resistance leads to excess androgen production (male hormone), negatively impacting ovulation. As the name suggests, genetic predisposition is hereditary. Inflammation is the body’s natural response to an injury or an infection. Chronic inflammation can cause the body to produce excess androgens or cytokines(fat tissue inflammation), leading to increased insulin resistance and causing hormonal changes and irregular menstrual cycles.
The symptoms of PCOS are irregular menstrual cycles, excessive hair growth on the face, chest, and back (hirsutism), polycystic ovaries, skin changes such as acne, oily skin or skin tags, male-pattern baldness or thinning hair, weight gain and challenges losing weight. Infertility is also a symptom of PCOS.
How Does PCOS Affect Pregnancy?
In India, the PCOS infertility rate ranges between 3.5-22.5%. Patients with PCOS suffer from hormonal imbalances that make ovulation challenging. PCOS can interfere with normal ovarian function and hormone production. It can also lead to the thickening of the endometrial lining, causing disruption during implantation. The associated health problems like obesity and metabolic syndrome are also known to increase the PCOS infertility rate.
How Effective is Artificial Reproductive Technology (ART) in PCOS Patients?
While there are a bunch of alternative methods to conceive, the PCOS pregnancy success rate in the case of Intrauterine Insemination (IUI) and IVF is around 70%. While both methods are associated with ART, their approach differs. The significant difference lies in the process of fertilisation. In the case of IUI, the semen is collected and processed to improve its motility and then injected into the uterus for a natural pregnancy. In contrast, IVF treatment includes retrieving and fertilising an egg in a laboratory setting.
Treatment choice depends on many factors like age , tubal patency , semen parameters and previous treatment response. . The PCOS IVF success rate also depends on the expertise of the IVF specialist. If you are a PCOS patient and are having difficulty conceiving, look for the best IVF doctor in Delhi. IVF requires as much emotional and psychological support as medical treatment. An experienced, empathetic, and supportive doctor can offer guidance and support throughout the journey.
Final Thoughts
While PCOS causes innumerable challenges, it’s crucial to remember that with the proper support and medical intervention, many women with PCOS can successfully get pregnant. Through a combination of lifestyle changes, medication, ART techniques, and the best fertility specialist in Delhi, PCOS patients can overcome infertility and experience the joy of parenthood.
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